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Mgbochi mmadụ s100 β Antibody, Mouse Monoclonal

Nkọwa dị mkpirikpi:

Ịdị ọcha Affinity-chromatography Isotype Ekpebibeghị
Ụdị ndị ọbịa Òké Ụdị mmeghachi omume Mmadụ
Ngwa Chemiluminescent Immunoassay (CLIA)

Nkọwa ngwaahịa

Mkpado ngwaahịa

Nkọwa ngwaahịa

Ozi izugbe
S100B bụ protein na-ejikọta calcium, nke a na-ezobe na astrocytes.Ọ bụ obere protein cytosolic dimeric (21 kDa) nke nwere ụdọ ββ ma ọ bụ αβ.S100B na-etinye aka n'ọtụtụ ọrụ nchịkwa intracellular na extracellular.
N'ime afọ iri gara aga, S100B apụtala dị ka onye ndoro-ndoro anya biomarker nke mgbochi ụbụrụ ọbara (BBB) ​​na mmerụ ahụ CNS.Ọkwa S100B dị elu na-egosipụta n'ụzọ ziri ezi ọnụnọ nke ọnọdụ neuropathological gụnyere mmerụ ahụ isi na-akpata na ọrịa neurodegenerative.Ọkwa S100B nkịtị na-ewepụ ntụkwasị obi dị ukwuu na-ewepu isi pathology CNS.A kọwokwa serum S100B dị ka akara bara uru maka nchọpụta mmalite nke metastases nke melanoma na nsogbu ụbụrụ site na mmerụ isi, ịwa ahụ obi, na nnukwu ọrịa strok.

Njirimara

Nkwanye ụzọ abụọ CLIA (Nchọpụta-Nchọpụta):
5H2-3 ~ 22G7-5
22G7-5 ~ 5H2-3
Ịdị ọcha > 95% dị ka SDS-PAGE siri kpebie.
Nhazi ihe nchekwa 20mM PB, 150mM NaCl, 0.1% Proclin 300, pH7.4
Nchekwa Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20 ℃ ruo -80 ℃ mgbe ị na-enweta ya.
Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma.

Ntụnyere asọmpi

Nkọwa

Ozi ịtụ

Aha ngwaahịa Nwamba.Mba NJ mmepụta oyiri
s100 β AB0061-1 5H2-3
AB0061-2 22G7-5
AB0061-3 21A6-1

Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.

Nkọwapụta

1. Ostendorp T , Leclerc E , Galichet A , et al.Nghọta nhazi na arụ ọrụ na ntinye RAGE site na multimeric S100B[J].Akwụkwọ akụkọ EMBO, 2007, 26 (16): 3868-3878.

2. R, D, Rothorl, et al.Ọkwa serum S100B dị elu maka ndị ọrịa trauma na-enweghị mmerụ isi.[J].Neurosurgery, 2001.


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