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Anti-mmadụ PIVKA -II Antibody, Mouse Monoclonal

Nkọwa dị mkpirikpi:

Ịdị ọcha Kọlụm mmekọ Protein A/G Isotype IgG1 akpa
Ụdị ndị ọbịa Òké Ụdị mmeghachi omume Mmadụ
Ngwa Immunochromatography (IC)/ Chemiluminescent Immunoassay (CLIA)

Nkọwa ngwaahịa

Mkpado ngwaahịa

Nkọwa ngwaahịa

Ozi izugbe
Protein na-ebute site na Vitamin K Absence ma ọ bụ onye na-emegide-II (PIVKA-II), nke a makwaara dị ka Des-γ-carboxy-prothrombin (DCP), bụ ụdị na-adịghị mma nke prothrombin.Dị ka ọ na-adịkarị, prothrombin's 10 glutamic acid residues (Glu) na ngalaba γ-carboxyglutamic acid (Gla) na ọnọdụ 6, 7, 14, 16, 19, 20,25, 26, 29 na 32 bụ γ-carboxylated na Gla site na vitamin. -K dabere γ- glutamyl carboxylase na imeju wee zoo ya na plasma.N'ime ndị ọrịa nwere carcinoma hepatocellular (HCC), γ-carboxylation nke prothrombin na-emebi PIVKA-II kama ịbụ prothrombin.A na-ahụta PIVKA-II dị ka onye na-ahụ maka biomarker na-arụ ọrụ nke ọma maka HCC.

Njirimara

Nkwanye ụzọ abụọ CLIA (Nchọpụta-Nchọpụta):
1E5-1 ~ 1D6-10
1E5-1 ~ 1E6-7
Ịdị ọcha > 95%, nke SDS-PAGE kpebiri
Nhazi ihe nchekwa 20mM PB, 150mM NaCl, 0.1% Proclin 300, pH7.4
Nchekwa Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20 ℃ ruo -80 ℃ mgbe ị na-enweta ya.
Maka nchekwa ogologo oge, biko wepụ ma chekwaa ya.Zenarị okirikiri oyi na-agbaze ugboro ugboro.

Nyocha ntụnyere

Nkọwa (1)
Nkọwa (2)

Ozi ịtụ

Aha ngwaahịa Nwamba.Mba NJ mmepụta oyiri
PIVKA- AB0009-1 1F4-5
AB0009-2 1E5-1
AB0009-3 1D6-10
AB0009-4 1E6-7

Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.

Nkọwapụta

1.Matsueda K , Yamamoto H , Yoshida Y , et al.Hepatoid carcinoma nke pancreas na-emepụta protein na-akpata site na enweghị vitamin K ma ọ bụ antagonist II (PIVKA-II) na α-fetoprotein (AFP) [J].Akwụkwọ akụkọ Gastroenterology, 2006, 41 (10): 1011-1019.

2.Viggiani, Valentina, Palombi, 等.Protein na-ebute site na enweghị vitamin K ma ọ bụ antagonist-II (PIVKA-II) mụbara kpọmkwem na ndị ọrịa hepatocellular carcinoma Italy.Akwụkwọ akụkọ Scandinavian nke Gastroenterology, 2016.

3.Simundic AM.Ndụmọdụ bara uru maka nyocha ọnụ ọgụgụ na ngosipụta data na akwụkwọ akụkọ Biochemia Medica[J].Biochemia Medica, 2012, 22(1).

4.Tartaglione S, Pecorella I, Zarrillo SR, et al.Protein na-ebute site na Vitamin K Absence II (PIVKA-II) dị ka onye nwere ike ime biomarker serological na ọrịa cancer pancreatic: nchọpụta pilot [J].Biochemia Medica, 2019, 29(2).


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