Anti-mmadụ GDF15 Antibody, Mouse Monoclonal
Nkọwa ngwaahịa
Ozi izugbe
Uto-iche ihe 15 (GDF15), nke a makwaara dị ka MIC-1, bụ onye zoro ezo nke ihe na-agbanwe uto uto (TGF) -β superfamily, dị ka ihe na-achịkwa ihe mgbochi hypertrophic n'ime obi.GDF-15 / GDF15 adịghị egosipụta n'ime obi ndị toro eto nkịtị mana a na-akpali ya na nzaghachi na ọnọdụ ndị na-akwalite hypertrophy na cardiomyopathy dilated ma na-egosipụta ya nke ukwuu na imeju.GDF-15 / GDF15 nwere ọrụ n'ịhazi ụzọ mkpali na apoptotic na anụ ahụ merụrụ ahụ na n'oge usoro ọrịa.GDF-15 / GDF15 na-arụ ọrụ dị ka ihe mbụ molecules nke a na-ahazi na ebe a na-akpachapụ anya iji hapụ ngalaba C-terminal nwere njirimara njirimara nke 7 echekwabara cysteine na protein tozuru okè.GDF-15/GDF15 ikwubiga okwu ókè na-esite na ngalaba erythroid gbasaara na-enye aka na ibufe ígwè na ọrịa thalassaemia site na igbochi okwu hepcidin.
Njirimara
| Nkwanye ụzọ abụọ | CLIA (Nchọpụta-Nchọpụta): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
| Ịdị ọcha | > 95%, nke SDS-PAGE kpebiri |
| Nhazi ihe nchekwa | PBS, pH7.4. |
| Nchekwa | Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20 ℃ ruo -80 ℃ mgbe ị na-enweta ya. Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma. |
Ntụnyere asọmpi
Ozi ịtụ
| Aha ngwaahịa | Nwamba.Mba | NJ mmepụta oyiri |
| GDF-15 | AB0038-1 | 3A2-1 |
| AB0038-2 | 23F1-5 | |
| AB0038-3 | 6C1-9 | |
| AB0038-4 | 4D5-8 |
Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.
Nkọwapụta
1.Wollert KC, Kempf T, Peter T, et al.Uru amụma nke Uto-Ihe dị iche iche-15 n'ime ndị ọrịa nwere ọrịa na-abụghị ST-Elevation Acute Coronary Syndrome[J].Mgbasa, 2007, 115 (8): 962-971.
2.Kempf T, Haehling SV, Peter T, et al.Uru prognostic nke ihe dị iche iche nke uto-15 na ndị ọrịa nwere nkụchi obi na-adịghị ala ala.[J].Akwụkwọ akụkọ nke American College of Cardiology, 2007, 50 (11): 1054-1060.
