Ozi izugbe
Ihe na-eto eto nke vaskụla endothelial (VEGF), nke a makwaara dị ka vaskụla permeability factor (VPF) na VEGF-A, bụ onye mgbasa ozi dị ike nke ma angiogenesis na vasculogenesis na nwa ebu n'afọ na okenye.Ọ bụ otu n'ime ezinaụlọ na-eto eto nke na-enweta platelet (PDGF)/vaskụla endothelial growth factor (VEGF) na-adịkarịkwa dị ka homodimer jikọtara disulfide.VEGF-A protein bụ glycosylated mitogen nke na-arụ ọrụ kpọmkwem na sel endothelial ma nwee mmetụta dị iche iche, gụnyere mgbasa ozi na-abawanye ụba nke vaskụla permeability, na-ebute angiogenesis, vasculogenesis na sel endothelial, na-akwalite ịkwaga cell, na-egbochi apoptosis na uto tumor.VEGF-A protein bụkwa vasodilator nke na-eme ka microvascular permeability dị elu, ya mere a na-akpọ ya na mbụ dị ka ihe na-eme ka ọkpụkpụ vaskụla.
Nkwanye ụzọ abụọ | CLIA (Nchọpụta-Nchọpụta): 12A4-7 ~ 5F6-2 2B4-6 ~ 5F6-2 |
Ịdị ọcha | > 95%, nke SDS-PAGE kpebiri |
Nhazi ihe nchekwa | PBS, pH7.4. |
Nchekwa | Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20 ℃ ruo -80 ℃ mgbe ị na-enweta ya. Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma. |
Aha ngwaahịa | Nwamba.Mba | NJ mmepụta oyiri |
VEGFA | AB0042-1 | 2B4-6 |
AB0042-2 | 12A4-7 | |
AB0042-3 | 5F6-2 |
Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.
1.Tammela T , Enholm B , Alitalo K , et al.Ihe omumu ihe omumu nke vaskụla endothelial uto ihe [J].Nnyocha obi obi, 2005, 65 (3): 550.
2.Wolfgang, Lieb, Radwan, et al.Ihe na-eto eto nke vascular endothelial, onye na-anabata ya soluble, na ihe na-eto eto hepatocyte: ụlọ ọgwụ na mkpụrụ ndụ ihe nketa na-ejikọta ya na ọrụ vaskụla [J].Akwụkwọ akụkọ European Heart, 2009.