Anti-mmadụ SHBG mgbochi, Mouse Monoclonal
Nkọwa ngwaahịa
Ozi izugbe
Mmekọahụ homonụ na-ejikọta globulin (SHBG) bụ glycoprotein nke ihe dịka 80-100 kDa;ọ nwere oke mmekọrịta maka 17 beta-hydroxysteroid hormones dị ka testosterone na estradiol.SHBG
A na-ahazi itinye uche na plasma site, n'etiti ihe ndị ọzọ, nguzozi androgen/estrogen, homonụ thyroid, insulin na ihe nri nri.Ọ bụ protein njem kachasị mkpa maka estrogens na androgens n'ime ọbara dị n'akụkụ.Ntinye uche SHBG bụ isi ihe na-ahazi nkesa ha n'etiti steeti ndị nwere protein na ndị nweere onwe ha.Mbelata nke SHBG Plasma bụ
emetụta ọtụtụ ọrịa dị iche iche, ọnụ ahịa dị elu dị na hyperthyroidism, hypogonadism, androgen insensitivity na imeju imeju na ụmụ nwoke.A na-ahụ ọkwa dị ala na myxoedema, hyperprolactinemia na ọrịa nke oke ọrụ androgen.Ntụle nke SHBG bara uru na nyocha nke nsogbu dị nro nke metabolism androgen ma na-enyere aka ịmata ụmụ nwanyị ndị nwere hirsutism bụ ndị nwere ike ịzaghachi ọgwụgwọ estrogen.
Njirimara
| Nkwanye ụzọ abụọ | CLIA (Nchọpụta-Nchọpụta): 3E10-1 ~ 3A10-5 3A10-5 ~ 3D8-2 |
| Ịdị ọcha | > 95%, nke SDS-PAGE kpebiri |
| Nhazi ihe nchekwa | PBS, pH7.4. |
| Nchekwa | Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20 ℃ ruo -80 ℃ mgbe ị na-enweta ya. Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma. |
Ntụnyere asọmpi
Ozi ịtụ
| Aha ngwaahịa | Nwamba.Mba | NJ mmepụta oyiri |
| SHBG | AB0030-1 | 3A10-5 |
| AB0030-2 | 3E10-1 | |
| AB0030-3 | 3D8-2 |
Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.
Nkọwapụta
1. Selby C. Mmekọahụ homonụ na-ejikọta globulin: mmalite, ọrụ na mkpa ụlọ ọgwụ.Ann Clin Biochem 1990;27:532-541.
2. Pugeat M, Crave JC, Tourniare J, et al.Uru ụlọ ọgwụ nke homonụ mmekọahụ na-ejikọta nha globulin.Horm Res 1996; 45 (3-5): 148-155 .
