Mgbochi mmadụ IL6, Mouse Monoclonal
Nkọwa ngwaahịa
Ozi izugbe
Interleukin-6 (IL-6) bụ multifunctional α-helical cytokine nke na-achịkwa uto cell na ọdịiche dị iche iche nke anụ ahụ dị iche iche, nke a maara karịsịa maka ọrụ ya na nzaghachi mgbochi na mmeghachi omume dị ukwuu.A na-ezobe protein IL-6 site na ụdị sel dị iche iche gụnyere mkpụrụ ndụ T na macrophages dị ka molecule phosphorylated na variably glycosylated.Ọ na-eme ihe site na onye na-anabata heterodimeric nke mejupụtara IL-6R nke na-enweghị ngalaba tyrosine / kinase ma jikọta IL-6 na njikọ dị ala, ma gosipụta glycoprotein 130 (gp130) nke na-ejikọta IL-6.IL-6R mgbagwoju nwere nnukwu mmekọrịta ma si otú a na-atụgharị akara.IL-6 na-etinyekwa aka na hematopoiesis, ọkpụkpụ metabolism, na ọganihu ọrịa cancer, ma kọwapụtara ya dị ka ọrụ dị mkpa n'ịduzi mgbanwe site na ihe ebumpụta ụwa gaa na nchebe enwetara.
Njirimara
| Nkwanye ụzọ abụọ | CLIA (Nchọpụta-Nchọpụta): 1B1-4 ~ 2E4-1 2E4-1 ~ 1B1-4 |
| Ịdị ọcha | > 95%, nke SDS-PAGE kpebiri |
| Nhazi ihe nchekwa | PBS, pH7.4. |
| Nchekwa | Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20 ℃ ruo -80 ℃ mgbe ị na-enweta ya. Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma. |
Ntụnyere asọmpi
Nyocha njikọ -<120pg>
Nyocha njikọ -1.5-5000pg / ml
Ozi ịtụ
| Aha ngwaahịa | Nwamba.Mba | NJ mmepụta oyiri |
| IL6 | AB0001-1 | 1B1-4 |
| AB0001-2 | 2E4-1 | |
| AB0001-3 | 2C3-1 |
Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.
Nkọwapụta
1.Zhong Z, Darnell ZW, Jr. Stat3: onye òtù ezinụlọ STAT na-arụ ọrụ site na tyrosine phosphorylation na nzaghachi na-eto eto epidermal na interleukin-6 [J].Sayensị, 1994.
2.J, Bauer, F, et al.Interleukin-6 na ọgwụ ahụike [J].Akụkọ banyere Hematology, 1991.
