Ozi izugbe
A na-ekewa Alpha-fetoprotein (AFP) dị ka onye so na albuminoid gene superfamily nke nwere albumin, AFP, vitamin D (Gc) protein na alfa-albumin.AFP bụ glycoprotein nke amino acid 591 na ihe mejupụtara ya.AFP bụ otu n'ime protein dị iche iche akọwapụtara n'embrayo na ọ bụkwa protein na-ahụ maka serum dị ka mmalite ndụ embrayo mmadụ dị ka otu ọnwa, mgbe albumin na transferrin dị na obere ntakịrị.A na-emepụta ya na mbụ n'ime mmadụ site na nkochi imeju nkochi imeju (1-2 ọnwa) ma emesịa na-abụkarị na imeju.A na-emepụta obere ego AFP site na traktị GI nke echiche mmadụ.E gosiputara na AFP nwere ike ịpụta ọzọ na serum n'ogo dị elu na ndụ ndị okenye na-ejikọta ya na usoro mweghachi nkịtị yana na uto ọjọọ.Alfa-fetoprotein (AFP) bụ akara a kapịrị ọnụ maka carcinoma hepatocellular (HCC), teratoblastomas, na ntụpọ akwara akwara (NTD).
Nkwanye ụzọ abụọ | CLIA (Nchọpụta-Nchọpụta): 3C8-6 ~ 11D1-2 8A3-7 ~ 11D1-2 |
Ịdị ọcha | > 95%, nke SDS-PAGE kpebiri |
Nhazi ihe nchekwa | PBS, pH7.4. |
Nchekwa | Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20℃ruo -80℃n'ịnata. Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma. |
Aha ngwaahịa | Nwamba.Mba | NJ mmepụta oyiri |
AFP | AB0069-1 | 11D1-2 |
AB0069-2 | 3C8-6 | |
AB0069-3 | 8A3-7 |
Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.
1.Mizejewski GJ.(2001) Ọdịdị na ọrụ Alfa-fetoprotein: mkpa maka Isoforms, Epitopes, na Conformational Variants.Exp Biol Med.226 (5): 377-408 .
2.Tomasi TB, et al.(1977) Ọdịdị na ọrụ nke Alpha-Fetoprotein.Nyochaa ọgwụ kwa afọ.28: 453-65 .
3.Leguy MC, et al.(2011) Ntụle nke AFP na mmiri ọmụmụ: ntụnyere usoro atọ akpaaka.Ann Biol Clin.69 (4): 441-6 .