Mgbochi mmadụ RBP4 mgbochi mmadụ, Mouse Monoclonal
Nkọwa ngwaahịa
Ozi izugbe
Retinol-binding protein 4 (RBP4) bụ onye na-ebu maka retinol (nke a makwaara dị ka vitamin A), ọ bụkwa ya na-ahụ maka ntụgharị nke retinol na-adịghị akwụsị akwụsị na nke na-adịghị edozi ahụ na ngwọta mmiri n'ime ihe siri ike na nke soluble na plasma site na mmekọrịta ha siri ike.Dịka onye so na ezinụlọ lipocalin superfamily, RBP4 nwere usoro β-barrel nke nwere oghere akọwapụtara nke ọma na-ezobe na imeju, ma n'aka nke ya na-ebuga retinol site na ụlọ ahịa imeju gaa na anụ ahụ dị n'akụkụ.Na plasma, RBP4-retinol complex na-emekọrịta ihe na transthyretin (TTR), nke a na-ejikọta ya dị oké mkpa maka igbochi nkwụsị nke RBP4 site na glomeruli akụrụ.RBP4 gosipụtara site na isi iyi ectopic na-ebuga retinol nke ọma na anya, ụkọ ya na-emetụta ọhụụ abalị nke ukwuu.N'oge na-adịbeghị anya, RBP4 dị ka adipokine, ka a na-egosipụta na anụ ahụ adipose ma jikọta ya na oke ibu, nkwụsị insulin (IR) na ụdị ọrịa shuga 2 (T2DM).
Njirimara
| Nkwanye ụzọ abụọ | CLIA (Nchọpụta-Nchọpụta): 9D11-8 ~ 3D4-1 3C8-1 ~ 3D4-1 |
| Ịdị ọcha | > 95% dị ka SDS-PAGE siri kpebie. |
| Nhazi ihe nchekwa | PBS, pH7.4. |
| Nchekwa | Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20 ℃ ruo -80 ℃ mgbe ị na-enweta ya. Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma. |
Ntụnyere asọmpi
Ozi ịtụ
| Aha ngwaahịa | Nwamba.Mba | NJ mmepụta oyiri |
| RBP4 | AB0032-1 | 9D11-8 |
| AB0032-2 | 3C8-1 | |
| AB0032-3 | 3D4-1 | |
| AB0032-4 | 1C6-1 |
Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.
Nkọwapụta
1.Aiwei YB , Vijayalakshmi V , Bodles AM , et al.Retinol na-ejikọta protein 4 n'ime mmadụ: mmekọrịta na nguzogide insulin, mbufụt, na nzaghachi na pioglitazone.J Clin Endocrinol Metab (7): 2590-2597.
2.Haider DG , Karin S , Gerhard P , et al.Ọbara retinol na-ekekọta protein 4 na-ebelata ka ọ gafechara n'ihe gbasara oke ibu.[J].Akwụkwọ akụkọ nke Clinical Endocrinology & Metabolism (3): 1168-71.
