Anti-mmadụ Her2 Antibody, Mouse Monoclonal
Nkọwa ngwaahịa
Ozi izugbe
Onye na-anabata ihe na-eto eto epidermal 2 (HER2), nke a makwaara dị ka ErbB2, NEU, na CD340, bụ ụdị I membrane glycoprotein ma bụrụ nke ezinụlọ ndị na-anabata epidermal growth factor (EGF).Protein HER2 enweghị ike ijikọ ihe ndị na-eto eto n'ihi enweghị ngalaba njikọ njikọ ligand nke ya ma gbochie ya nke ọma.Otú ọ dị, HER2 na-emepụta heterodimer na ndị òtù ezinụlọ ndị na-anabata EGF ndị ọzọ na-ejikọta ligand, ya mere na-eme ka njikọ ligand guzosie ike ma na-eme ka kinase-mediated activation nke ụmụ irighiri ihe dị n'okpuru.HER2 na-arụ ọrụ dị mkpa na mmepe, mmụba cell na ọdịiche.A kọwala mkpụrụ ndụ HER2 na-ejikọta ya na ọrịa ọjọọ yana amụma na-adịghị mma n'ọtụtụ carcinomas, gụnyere ara, prostate, ovarian, ọrịa cancer akpa ume na ihe ndị ọzọ.
Njirimara
| Nkwanye ụzọ abụọ | CLIA (Nchọpụta-Nchọpụta): 14-2~ 15-6 15-6 ~ 2-10 |
| Ịdị ọcha | > 95%, nke SDS-PAGE kpebiri |
| Nhazi ihe nchekwa | PBS, pH7.4. |
| Nchekwa | Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20 ℃ ruo -80 ℃ mgbe ị na-enweta ya. Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma. |
Ozi ịtụ
| Aha ngwaahịa | Nwamba.Mba | NJ mmepụta oyiri |
| Her2 | AB0078-1 | 14-2 |
| AB0078-2 | 15-6 | |
| AB0078-3 | 2-10 |
Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.
Nkọwapụta
1.Krawczyk N, et al.(2009) Ọnọdụ HER2 na mkpụrụ ndụ tumor na-ekesa na-adịgide adịgide mgbe ọgwụgwọ adjuvant nwere ike ịdị iche na ọkwa HER2 mbụ na ụbụrụ isi.Anticancer Res.29 (10): 4019-24.
