Ozi izugbe
Preeclampsia bụ nnukwu mgbagwoju anya nke sistemu afọ ime, nke na-eme na 3 - 5% nke ime ime, ọ bụkwa otu n'ime ihe na-ebute ọrịa ọrịa nne na nke ime nwa na ọnwụ n'ụwa niile.
A kọwara Preeclampsia dị ka mmalite ọbara mgbali elu na proteinuria ọhụrụ mgbe izu iri abụọ nke ime ime gasịrị.Ngosipụta ụlọ ọgwụ nke preeclampsia na usoro ọgwụgwọ ọrịa na-esote nwere ike ịdịgasị iche nke ukwuu, na-eme ka amụma, nyocha na nyocha nke ọganihu ọrịa siri ike.
E gosipụtara ihe ndị angiogenic (sFlt-1 na PlGF) na-arụ ọrụ dị mkpa na pathogenesis nke preeclampsia na ntinye ha na serum nke nne na-agbanwe ọbụna tupu mmalite nke ọrịa ahụ na-eme ka ha bụrụ ngwá ọrụ maka amụma na enyemaka na nchọpụta nke preeclampsia.
Nkwanye ụzọ abụọ | CLIA (Nchọpụta-Nchọpụta): 1E4-6 ~ 2A6-4 2A6-4 ~ 1E4-6 |
Ịdị ọcha | > 95% dị ka SDS-PAGE siri kpebie. |
Nhazi ihe nchekwa | PBS, pH7.4. |
Nchekwa | Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20 ℃ ruo -80 ℃ mgbe ị na-enweta ya. Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma. |
Aha ngwaahịa | Nwamba.Mba | NJ mmepụta oyiri |
sFlt-1 | AB0029-1 | 1E4-6 |
AB0029-2 | 2A6-4 | |
AB0029-3 | 2H1-5 | |
AB0029-4 | 4D9-10 |
Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.
1.Stepan H , Geide A , Faber R .Soluble fms-dị ka tyrosine kinase 1.[J].N Engl J Med, 2004, 351(21):2241-2242.
2.Kleinrouweler CE , Wiegerinck M , Ris-Stalpers C , et al.Ịdị mma nke ihe na-eto eto placental na-ekesa, vaskụla endothelial growth factor, soluble fms-dị ka tyrosine kinase 1 na soluble endoglin na amụma pre-eclampsia: nyochaa nhazi na meta-analysis.[J].Bjog An International Journal of Obstetrics & Gynaecology, 2012, 119(7):778-787.