Ozi izugbe
Pepsinogen bụ pro-ụdị pepsin ma na-emepụta n'ime afo site na isi sel.A na-ezobe akụkụ bụ isi nke pepsinogen n'ime lumen gastric mana enwere ike ịhụ ntakịrị n'ime ọbara.Achọpụtala mgbanwe na mkpokọta pepsinogen serum na ọrịa Helicobacter pylori (H. Pylori), ọrịa ọnya peptic, gastritis, na ọrịa kansa afọ.Enwere ike nweta nyocha nke ọma karịa site na ịtụ nha pepsinogen I/II.
Nkwanye ụzọ abụọ | CLIA (Nchọpụta-Nchọpụta): 3A7-13 ~ 2D4-4 |
Ịdị ọcha | > 95%, nke SDS-PAGE kpebiri |
Nhazi ihe nchekwa | 20mM PB, 150mM NaCl, 0.1% Proclin 300, pH7.4 |
Nchekwa | Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20 ℃ ruo -80 ℃ mgbe ị na-enweta ya. Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma. |
Aha ngwaahịa | Nwamba.Mba | NJ mmepụta oyiri |
PGII | AB0006-1 | 3A7-13 |
AB0006-2 | 2C2-4-1 | |
AB0006-3 | 2D4-4 |
Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.
1.Kodoi A , Haruma K , Yoshihara M , et al.[Ihe ọmụmụ ụlọ ọgwụ nke pepsinogen I na II na-emepụta carcinomas gastric].[J].Nihon Shokakibyo Gakkai zasshi = Akwụkwọ akụkọ Japanese nke gastro-enterology, 1993, 90(12):2971.
2.Xiao-Mei L, Xiu Z, Ai-Min Z.Ọmụmụ ihe gbasara ụlọ ọgwụ nke serum pepsinogen maka njirimara ọrịa kansa afọ na ọnya afọ precancerous [J].Mgbari ọgbara ọhụrụ & Ntinye aka, 2017.