Ozi izugbe
Influenza, ma ọ bụ influenza, bụ ọrịa iku ume na-efe efe nke nje virus dị iche iche na-ebute.Mgbaàmà nke flu gụnyere ahụ mgbu na ahụ mgbu, isi ọwụwa, na ahụ ọkụ.Ụdị nje flu na-agbanwe mgbe nile ma na-akpatakarị nnukwu ọrịa flu.
Enwere ike kewaa influenza A n'ime ụdị subtypes dị iche iche dabere na nchikota protein abụọ na elu viral: hemagglutinin (H) na neuraminidase (N).
Nkwanye ụzọ abụọ | IC(Nchọpụta-Nchọpụta):1B5-6 ~ 3A9-8 |
Ịdị ọcha | > 95%, nke SDS-PAGE kpebiri |
Nhazi ihe nchekwa | PBS, pH7.4. |
Nchekwa | Chekwaa ya n'okpuru ọnọdụ adịghị mma na -20℃ruo -80℃n'ịnata. Na-akwado iwebata protein n'ime obere nha maka nchekwa kacha mma. |
Aha ngwaahịa | Nwamba.Mba | NJ mmepụta oyiri |
Flu A | AB0023-1 | 1F10-1 |
AB0023-2 | 1B5-6 | |
AB0023-3 | 3A9-8 |
Mara: Bioantibody nwere ike ahaziri nha maka mkpa gị.
1.Senne DA, Panigrahy B, Kawaoka Y, et al.Nnyocha nke usoro ebe mkpochapụ hemagglutinin (HA) nke H5 na H7 nje influenza avian: usoro amino acid na saịtị mgbawa HA dị ka akara nke ikike nje.Ọrịa Avian, 1996, 40 (2): 425-437.
2.Benton DJ, Gamblin SJ, Rosenthal PB, et al.Mgbanwe nhazi na influenza haemagglutinin na membrane fusion pH[J].okike, 2020:1-4 .
3.1.Urai C, Wanpen C. Evolution of Therapeutic Antibodies, Influenza Virus Biology, Influenza, and Influenza Immunotherapy.Ụlọ ọrụ Biomed Res Int.2018.
4.2.Florian K. Nzaghachi mgbochi mmadụ na nje nje influenza A na ịgba ọgwụ mgbochi ọrịa.Nature reviews immunology.2019, 19, 383-397.